aggravation – Communicable Diseases Research

Identification and characterization of the anti-SARS-CoV-2 activity of cationic amphiphilic steroidal compounds

양이온성 양친매성 스테로이드 화합물의 항 SARS-CoV-2 활성의 확인 및 특성화

Article

Published on 2022-12-012022-09-11
Journal: Virulence
[Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 치료제,

Drug repurposing for the treatment of COVID-19

COVID-19 치료를 위한 약물 용도 변경

Review

Published on 2022-07-012022-09-11
Journal: Journal of pharmacological sciences
[Category] COVID19(2023년), SARS, 변종, 신약개발, 치료법, 치료제,

[키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age aggravation approved Cancer cardiomyocyte cardiovascular disease coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 diabetes drug Drug repurposing Eco-pharma global effort global efforts heart failure hypertension increase mammalian cells mechanism Mortality NADPH NADPH oxidase outcome Patient prevalent protein-protein interaction Protein–protein interaction receptor receptor potential reported Research risk Safe SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe COVID-19 severity of COVID-19 shown therapeutic therapeutic agent therapeutic agents Transient Transient receptor potential channel. Treatment vaccine-resistant variant Vaccine-resistant variants virus Wuhan Wuhan, China
[DOI] 10.1016/j.jphs.2022.04.007 PMC 바로가기 [Article Type] Review

Analysis of COVID-19 inpatients in France during first lockdown of 2020 using explainability methods

설명 가능성 방법을 사용하여 2020년 첫 번째 폐쇄 기간 동안 프랑스의 COVID-19 입원 환자 분석

Article

Published on 2022-06-012022-09-11
Journal: Medical & biological engineering & computing
[Category] COVID19(2023년), SARS, 치료기술,

[키워드] Abstract age age and gender aggravation analyzed artificial intelligence AUC Care Chest CT COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients CRP Definition Effect Effects eosinophils Explainable artificial intelligence facilitated feature Features First wave France group high risk hospital Hospital stay identify in-depth analysis Inpatient Inpatients Instance selection intensive care units lockdown machine machine learning Machine learning. medical protocol medium MOST no risk O2 Saturation patients patients hospitalized risk risk factor robust ROC saturation score significantly spring stratified subgroup typology variable were used
[DOI] 10.1007/s11517-022-02540-0 PMC 바로가기 [Article Type] Article

Assessment of Recovery Time, Worsening, and Death among Inpatients and Outpatients with COVID-19, Treated with Hydroxychloroquine or Chloroquine plus Azithromycin Combination in Burkina Faso

부르키나파소에서 하이드록시클로로퀸 또는 클로로퀸과 아지트로마이신 조합으로 치료한 COVID-19 입원 환자 및 외래 환자의 회복 시간, 악화 및 사망 평가

Observational Study

Published on 2022-05-012022-09-11
Journal: International Journal of Infectious Diseases
[Category] COVID19(2023년), SARS, 임상, 치료제,

The Association of Work-related Stress According to the Demand–Control Model With Aggravation of Pre-existing Disease During the First State of COVID-19 Emergency in Japan

Original Article

Published on 2021-12-052022-10-30
Journal: Journal of Epidemiology
[Category] COVID-19, MERS, SARS,

Regulatory T Cells as Predictors of Clinical Course in Hospitalised COVID-19 Patients

입원한 COVID-19 환자의 임상 경과를 예측하는 조절 T 세포

Immunology

Published on 2021-12-022022-09-11
Journal: Frontiers in Immunology
[Category] SARS, 바이오마커, 진단,

[키워드] affected aggravation an area Analysis association AUC baseline CD4 circulating circulating cell clinical clinical evolution Clinical severity Combination correlated COVID-19 COVID-19 severity described Disease progression disease severity dysfunction dysregulation FiO2 flow cytometry Gender Hospital admission Hospitalization Host immune response hyper-inflammation identify immunophenotype inflammation markers lymphocyte lymphopenia management outcome PaO2 PaO2/FiO2 ratio parameter Patient Patient management performed peripheral Peripheral blood Phenotypic analysis predict presenting Probability progression reduced Regression analyses Regulatory Regulatory T cell regulatory T cells respiratory capacity Result risk ROC Curve SARS-COV-2 infection severe COVID-19 severe disease severity severity of COVID-19 shown significantly significantly higher Stratification subpopulation Support T cell T cell dysregulation T cell subset T cell subtypes T cells Th1 Ventilation WHO worsened worsening
[DOI] 10.3389/fimmu.2021.789735 PMC 바로가기 [Article Type] Immunology

COVID-19 and metabolic disease: mechanisms and clinical management

COVID-19 및 대사성 질환: 메커니즘 및 임상 관리

Review

Published on 2021-11-012022-09-11
Journal: The lancet. Diabetes & endocrinology
[Category] Fulltext, MERS, 유전자 메커니즘, 임상, 진단,

Clinical characteristics and potential factors for recurrence of positive SARS-CoV-2 RNA in convalescent patients: a retrospective cohort study

회복기 환자에서 양성 SARS-CoV-2 RNA의 재발에 대한 임상적 특징 및 잠재적 요인: 후향적 코호트 연구

Article

Published on 2021-08-012022-09-11
Journal: Clinical and experimental medicine
[Category] MERS, SARS, 진단, 치료기술,

[키워드] aggravation antibody carried Characteristics clinical Clinical characteristics Clinical features clinical records Clinical significance close contact collected convalescent coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 patient Cytokines demographic data discharged discharged patient disease evaluate Factor family members Features Follow-up hospital Hospitalization IgG and IgM IgM antibodies infectiousness Inflammatory cytokine Inflammatory cytokines Laboratory laboratory findings lead lymphocyte Lymphocyte subset Lymphocyte subsets negative RT-PCR no significant difference Patient patients positive positive RT-PCR prolonged viral shedding recurrence Recurrent Recurrent positive viral RNA retrospective cohort study Retrospective study RT-PCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RT-PCR significantly significantly lower symptoms of COVID-19 telephone the patient titer Transmission two group two groups Viral viral shedding Viral shedding.
[DOI] 10.1007/s10238-021-00687-y PMC 바로가기 [Article Type] Article

Clinical laboratory evaluation of COVID-19

COVID-19의 임상 실험실 평가

Review

Published on 2021-08-012022-09-11
Journal: Clinica chimica acta; international journal of cli
[Category] SARS, 바이오마커, 치료기술,

[키워드] activated aggravation ALT amplification Antigen antigen test antigen tests AST Biomarker Cancer cardiovascular disease caused chronic respiratory disease clinical laboratory clinically suspected complement COVID-19 COVID-19 patient critical cases CRP Cytokines D-dimer death decrease diabetes diagnosing Diagnosis Diseases effective Evidence evidence of example false false-negative ferritin hypertension identify IgA IgG IgM IL-6 independent risk factor Indicator Infection Infectious disease Inflammation inflammatory biomarkers Laboratory laboratory diagnosis LDH leukocytes lymphocyte Lymphocytes moderate moderate to severe neutrophil Neutrophils nucleic acid nucleic acid amplification testing obesity pathogenic progression Respiratory disease SAA SARS-CoV-2 SARS-CoV-2 nucleic acid SARS-CoV-2. Sequencing severe disease Severe infection specific antibodies specific antibody the disease TNF-α troponin I underlying disease underlying diseases urea viral loads
[DOI] 10.1016/j.cca.2021.04.022 PMC 바로가기 [Article Type] Review

Dietary Habits before and during the COVID-19 Epidemic in Selected European Countries

일부 유럽 국가에서 COVID-19 전염병 이전과 동안의 식습관

Clinical Trial

Published on 2021-05-162022-08-13
Journal: Nutrients
[Category] SARS, 임상,